Dyslipidemia can indirectly lead to heart failure. As the blood vessels become more clogged, the heart is unable to move enough blood through the circulatory system in response to your body’s demands. Either it can’t contract with the proper amount of force, or it can’t relax, allowing the chamber to fill with the blood returning from the lungs. In either case, the blood simply backs up and causes problems.
When the left side of the heart fails, fluid in the blood is forced to move from the blood vessels into the air spaces of the lung itself. This is known as pulmonary edema and is experienced by the patient as difficulty in breathing, and can be seen on a chest X-ray.
The extra volume of blood in the lungs also means that the right ventricle has to pump against an increased pressure. When the pressure is high enough that it can no longer do this, blood backs up into the rest of the body. The most vulnerable points in the body are those farthest away from the heart, such as the feet, where fluid is forced out of the blood stream and into the tissues. Therefore, a failing right ventricle often leads to swollen feet and ankles.